Shenzhen Wenzhi Bio-Technology Co.,Ltd
Shenzhen Wenzhi Bio-Technology Co.,Ltd
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Home>Products>Female Steroids>Potent Progesterone Female Steroids Chlormadinone Acetate Powder 302-22-7

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  • Potent Progesterone Female Steroids Chlormadinone Acetate Powder 302-22-7
  • Potent Progesterone Female Steroids Chlormadinone Acetate Powder 302-22-7
  • Potent Progesterone Female Steroids Chlormadinone Acetate Powder 302-22-7
  • Potent Progesterone Female Steroids Chlormadinone Acetate Powder 302-22-7

Potent Progesterone Female Steroids Chlormadinone Acetate Powder 302-22-7

  • Haiwen Female Steroids Chlormadinone Acetate Powder
  • Female Steroids Chlormadinone Acetate Powder

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  • GMP,SGS,UKAS,ISO
  • Negotiable
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  • foil bag or as your requirement
  • Within 1-2 working days upon receipt payment
  • T/T, Western union, MoneyGram
  • 1000kgs/month
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Shenzhen Wenzhi Bio-Technology Co.,Ltd

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Product Description

Potent Progesterone Female Steroids Chlormadinone Acetate Powder 302-22-7

Chlormadinone acetate Powder Description:
Chlormadinone acetate , sometimes abbreviated as CMA, is a steroidal progestin with additional antiandrogen and antigonadotropic (and thus also antiestrogenic) effects.

Chlormadinone acetate has a strong progestogenic effect about one-third higher than that of progesterone and may vary depending on the previous effect of an estrogen, i.e., estrogens may promote the formation of progesterone receptors and proliferation of the endometrium.

Like progesterone, it is anti-estrogenic and has no partial androgenic effect (at the doses used for contraception and HRT). In contrast to progesterone, it has a slight glucocorticoid effect, a pronounced anti-androgenic effect and no anti-mineralocorticoid effect. No pregnancy-maintaining effect of CMA has been demonstrated in humans.

The anti-androgenic effect of CMA is presumed to be the result of both its binding to androgen receptors competitively inhibiting the effect of endogenous testosterone and dihydrotestosterone and the competitive inhibition of 5-reductase. In this respect, dosing of CMA is crucial; agonistic effects are observed when doses are increased from those optimal for an antagonistic effect.

Chlormadinone acetate has a strong anti-gonadotropic effect, through negative feedback on gonadotropin secretion, and has been used for more than 20 years alone for contraception in arterial risk patients. The clinical and metabolic tolerability of CMA has been demonstrated in numerous clinical studies with duration of treatment of up to 2.5 years.

Chlormadinone acetate Powder Applications:
Chlormadinone acetate is used clinically as a hormonal contraceptive, and in part due to its lowering of estrogen levels, but also for improved effectiveness in contraception, chlormadinone is frequently combined with ethinyl estradiol for this purpose. It is the acetate ester of chlormadinone.

Chlormadinone acetate (CMA) is a derivative of naturally secreted progesterone that shows high affinity and activity at the progesterone receptor.

It has an anti-estrogenic effect and, in contrast to natural progesterone, shows moderate anti-androgenic properties. CMA acts by blocking androgen receptors in target organs and by reducing the activity of skin 5alpha-reductase.

It suppresses gonadotropin secretion and thereby reduces ovarian and adrenal androgen production. CMA shows high contraceptive efficacy by inhibiting ovulation due to its ability to suppress or disrupt endogenous gonadotropin secretion and, by this, inhibits follicular growth and maturation. In addition, it suppresses endometrial thickness and increases the viscosity of cervical mucus.

Place of Origin China
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Certification ISO9001, ISO14000, KOSHER,GMP
Minimum Order Quantity: 10g
Price: Negotiation
courier EMS, DHL, Fedex, UPS,TNT
Payment Terms: TT, West Union, Money Gram,Bitcoin
Supply Ability: 1000kg per month
Delivery date: Within 24 hours after receiving your payment
Packaging Details: Very discreet packages


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