99% Pramipexole Dihydrochloride Pharmaceutical Raw Material for Treat Parkinson

99% Pramipexole Dihydrochloride for Treat Parkinsons Disease CAS 104632-26-0

Quick Detail:

Product Name: Pramipexole
CAS: 104632-26-0
MF: C10H17N3S
MW: 211.33
Product Categories: All Inhibitors;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Chiral Reagents;Sulfur & Selenium Compounds;API;Mirapexin, Sifrol
Melting point : 288-290°C
Storage temp. : -20°C Freezer
Chemical Properties Off-White Solid
Quality Standards: CP/USP/BP/EP
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pramipexole Introduction:

Pramipexole is a dopamine agonist belonging to the same class of drugs as Cabergoline. The primary purpose of this drug is in the treatment of Parkinsons disease. Pramipexole is most commonly found under the brand names Sifrol, Mirapexin and Mirapex, although generics are also available. Mirapex is the most well known brand by Boehringer Ingelheim Pharmaceuticals. Along with treating Parkinsons, Pramipexole is also prescribed for the treatment of restless legs syndrome. The drug has also shown promising signs in the treatment of bipolar depression, although it has never officially held this label.
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pramipexole COA

Application :

Pramipexole is a dopamine agonist that directly correlates with the prolactin hormone. As dopamine levels in the body go up, prolactin levels go down. It does this by having a direct effect on the dopamine D3 receptor. Although it also acts on the D2 receptor its affinity for the D3 receptor is seven times greater than any existing dopamine agonist.

The effect of Pramipexole on the D3 receptor has a strong impact on the neurological system, which is why its used to treat Parkinsons disease and in some cases Alzheimers disease. Through acting on the D3 receptor, Pramipexole also affects a mans sexual interest and activity. Prolactin is in part directly responsible for a mans refractory period, which refers to the time it takes to recover from sexual activity so that performance can occur again. By lowering prolactin through an increase in dopamine, Pramipexole can directly reduce the refractory period resulting in the ability to perform sexually more frequently.

pramipexole USE:

Treating the signs and symptoms of Parkinson disease. It is also used to treat restless legs syndrome (RLS). It may also be used for other conditions as determined by your doctor.

Pramipexole is a dopamine agonist. Exactly how pramipexole works is not known. It may increase the action of certain chemical receptors in the brain.

pramipexole side effects

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Abnormal dreams; constipation; diarrhea; dizziness; drowsiness; dry mouth; headache; loss of appetite; nausea; stuffy nose; tiredness; trouble sleeping; weakness.
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99% Pramipexole Dihydrochloride Pharmaceutical Raw Material for Treat Parkinson Images