99% Pharmaceutical Materials Iron Chelator Deferasirox CAS 201530-41-8

99% Pharmaceutical Materials Iron Chelator Deferasirox CAS 201530-41-8

Product Description

Deferasirox For oral iron chelator 99.5% 201530-41-8

Product Name: Deferasirox
Synonyms: 4-[3,5-bis(2-hydroxyphenyl)-1,2,4-triazol-1-yl]benzoic acid;deferasirox;Benzoic acid, 4-[3,5-bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]-;Deferasirox for research;4-[3,5-Bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]benzoic Acid;CGP-72670;Exjade;ICL-670
CAS: 201530-41-8
MF: C21H15N3O4
MW: 373.3615
Chemical Properties White to Off-White Solid
Usage Orally active tridentate iron chelator

Deferasirox-------------------Description

1.Deferasirox is an oral iron chelator. Its main use is to reduce chronic iron overload in patients who are receiving long-term blood transfusions for conditions such as beta-thalassemia and other chronic anemias. It is the first oral medication approved in the USA for this purpose.

2.It was approved by the United States Food and Drug Administration (FDA) in November 2005.According to FDA (May 2007), renal failure and cytopenias have been reported in patients receiving deferasirox oral suspension tablets. It is approved in the European Union by the European Medicines Agency (EMA) for children 6 years and older for chronic iron overload from repeated blood transfusions.

COA

Properties of deferasirox

Two deferasirox molecules binding iron
The half-life of deferasirox is between 8 and 16 hours allowing once a day dosing. Two molecules of deferasirox are capable of binding to 1 atom of iron which are subsequently eliminated by fecal excretion. Its low molecular weight and high lipophilicity allows the drug to be taken orally unlike deferoxamine which has to be administered by IV route (intravenous infusion). Together with deferiprone, deferasirox seems to be capable of removing iron from cells (cardiac myocytes and hepatocytes) as well as removing iron from the blood.
.

The quality control process

1) Purchasing
Thorough market research, understand the price of raw materials and performance.To the procurement source to understand fully, and fully guarantee the quality of the procurement of raw materials.

2) Inspection
Four steps: sampling, sample pretreatment, measuring and data processing.

3) Producing

a) Each operator must do self-inspection of producs and make the corresponding inspection records.
b) Full-time inspectors through check the operator self-inspection, and review and sign in the corresponding record. Full-time inspection is responsible for inspection of finished product, and make the finished product incoming inspection records.

4) Before selling
Test result can be provided before selling.
Third-party detection institution is allowed if you are not satisfied with test results.

OUR ADWANTAGE:

High quality with competitive price:
1) Standard: Enterprise Standard
2) All Purity≥99%
3) We are manufacturer and can provide high quality products with factory price.

Fast and safe delivery
1) Parcel can be sent out in 24 hours after payment. Tracking number available
2) Secure and discreet shipment. Various transportation methods for your choice.
3) Customs pass rate ≥99%
4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe, and we have stock in there for transferring.

We have clients throughout the world.
1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
2) Market feedback and goods feedback will be appreciated, meeting customerss requirement is our responsibility.
3) High quality,competitive price,fast delivery ,first-class service gain the trust and praise from the customers.

99% Pharmaceutical Materials Iron Chelator Deferasirox CAS 201530-41-8 Images