CAS 1953-04-4 Pharmaceutical Raw Material Ingredient Rivastigmine Tartrate /

GMP Standard Ingredient Rivastigmine Tartrate / Galanthamine Hydrobromide CAS 1953-04-4

Basic information

Galantamine Hydrobromide
Galantamine Hydrobromide CAS: 1953-04-4
Galantamine Hydrobromide MF: C17H22BrNO3
Galantamine Hydrobromide MW: 368.27
Galantamine Hydrobromide EINECS: 217-780-5
Product Categories: Alkaloids;Alkaloids (Others);Biochemistry;Functional Products;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;APIs;Acetylcholine receptor;API;Chiral Reagents;Reminyl;Other APIs;Pharmaceutical intermediates
MP 256 °C
Storage temp. −20°C
Chemical Properties White to Off-White Powder
Usage A selective acetylcholinesterase inhibitor. A therapeutic agent for the treatment and prevention of Alzheimers disease and other diseases resulting from reduced neuronal metabolism.
Usage Alzheimer treatment;Cholinesterase inhibitor
Usage anticholinesterase, analgesic, antiAlzheimer

Galantamine Hydrobromide Description:

Galantamine hydrobromide is the hydrobromide salt of galantamine and is a cholinesterase inhibitor can be extracted from Amaryllidaceae Lycoris plant. The III-phase clinical trials in the United Kingdom in 1998 have showed that this drug had dual mechanism of action of both inhibiting acetylcholinesterase and regulating nicotinic receptors.

Therefore, galantamine can improve the cognitive abilities of Alzheimers patients and has been already applied as the drug of the treatment of mild to severe Alzheimers disease (AD) drugs and has entered into market in EC countries. "Chinese Pharmacopoeia" has included the both the raw material and injection of galantamine hydrobromide.

It is clinically mainly used for the treatment of poliomyelitis (polio) sequelae, muscular dystrophy and myasthenia gravis. It can be used to substitute neostigmine methyl-sulfate for antagonism of tubocurarine but with weak performance with the usage amount being ten times as high as the usage amount of neostigmine methyl-sulfate. Intravenous injection of 0.5 mg/kg of galantamine hydrobromide can quickly reverse the central anticholinergic effects caused through injection of scopolamine hydrobromide. It can also be used for treating children cerebral palsy, traumatic sensorimotor disorders, multiple neuritis and radiculitis.

Galantamine Hydrobromide Application :

It can be used for the treatment of neurological diseases and trauma-induced movement disorders, multiple neuritis, and radiculitis.
Cholinesterase inhibitors can reverse the process of scopolamine-induced amnesia.

COA

The quality control process

1) Purchasing
Thorough market research, understand the price of raw materials and performance.To the procurement source to understand fully, and fully guarantee the quality of the procurement of raw materials.

2) Inspection
Four steps: sampling, sample pretreatment, measuring and data processing.

3) Producing

a) Each operator must do self-inspection of producs and make the corresponding inspection records.
b) Full-time inspectors through check the operator self-inspection, and review and sign in the corresponding record. Full-time inspection is responsible for inspection of finished product, and make the finished product incoming inspection records.

4) Before selling
Test result can be provided before selling.
Third-party detection institution is allowed if you are not satisfied with test results.

OUR ADWANTAGE:

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1) Standard: Enterprise Standard
2) All Purity≥99%
3) We are manufacturer and can provide high quality products with factory price.

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We have clients throughout the world.
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2) Market feedback and goods feedback will be appreciated, meeting customerss requirement is our responsibility.
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CAS 1953-04-4 Pharmaceutical Raw Material Ingredient Rivastigmine Tartrate / Images