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Home>Products>Pharmaceutical Raw Material>99% High Purity Pharmaceutical Raw Material CAS 78755-81-4 Flumazenil

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  • 99% High Purity Pharmaceutical Raw Material CAS 78755-81-4 Flumazenil
  • 99% High Purity Pharmaceutical Raw Material CAS 78755-81-4 Flumazenil

99% High Purity Pharmaceutical Raw Material CAS 78755-81-4 Flumazenil

  • HW Pharmaceutical Raw Material
  • CAS: 78755-81-4 Pharmaceutical Raw Material

  • China
  • GMP,SGS,UKAS,ISO
  • Negotiable
  • Negotiable
  • foil bag or as your requirement
  • Within 1-2 working days upon receipt payment
  • T/T, Western union, MoneyGram
  • 1000kgs/month
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Shenzhen Wenzhi Bio-Technology Co.,Ltd

Shenzhen Wenzhi Bio-Technology Co.,LtdChina

  • Shenzhen Wenzhi Bio-Technology Co.,Ltd2020-07-10 09:46:19
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Product Details

CAS: 78755-81-4 Grade: USP/BP Assay: 99%
Molecular Formula: C15H14FN3O3 Molecular Weigh: 303.29 Character: white powder
Keywords: China Pharmaceutical Raw Materials, China Pharmaceutical Raw Materials manufacturers, Pharmaceutical Raw Materials catalog, Pharmaceutical Raw Materials

Product Description

99% Purity Pharmaceutical Raw Material CAS 78755-81-4 Flumazenil

Basic information

Product Name Flumazenil
Alias Flumazepil
CAS 78755-81-4
Purity 99.0%
Grade Pharmaceutical Grade
Brand Name STEROID
M.F. C15H14FN3O3
M.W. 303.29
Appearance White power
Storage Original package at cool dark place


2. Description:

Flumazenil (also known as flumazepil, code name Ro 15-1788) is a selective receptor antagonist primarily available by injection only, and the only GABAA negative allosteric modulator on the market today. It has antagonistic and antidote properties , through competitive inhibition.

It was first introduced in 1987 by Hoffmann-La Roche under the trade name Anexate, but only approved by the FDA on December 20, 1991. Flumazenil went off patent in 2008, so at present generic formulations of this drug are available. Intravenous flumazenil is primarily used to treat overdoses and to help reverse anesthesia. Administration of flumazenil by sublingual lozenge and topical cream has also been tested.

3. Application:

Flumazenil is of benefit in patients who become excessively drowsy.

It has been used as an antidote in the treatment of overdoses. There are many complications that must be taken into consideration when used in the acute care setting. These include lowered seizure threshold, agitation, and anxiousness. Flumazenils short half-life requires multiple doses and careful patient monitoring to prevent recurrence of overdose symptoms.

It is also sometimes used to reverse the effects after surgery in a manner similar to naloxones application to reverse the effect of opiates and opioids following surgery. This requires careful monitoring by an anesthesiologist due to potential side effects and serious risks associated with both over-administering flumazenil and the removal of patient life-support and monitoring equipment before the benzodiazepines have worn off (due to flumazenil masking their continued effect).

It may also be effective in reducing excessive daytime sleepiness while improving vigilance in primary hypersomnias, such as idiopathic hypersomnia.

It has also been used in hepatic encephalopathy, though results have been mixed.

The onset of action is rapid and usually effects are seen within one to two minutes. The peak effect is seen at six to ten minutes. The recommended dose for adults is 200 μg every 1-2 minutes until the effect is seen, to a maximum of 3 mg per hour. It is available as a clear, colourless solution for intravenous injection, containing 500 μg in 5 mL.

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2,5-dihydroxybenzoic acid 490-79-9
Lederfen 36330-85-5
Fenazox 61618-27-7
Diflunisal 22494-42-4
Feprazone 30748-29-9
Leflunomide 75706-12-6
Chlorfenamic Acid 13278-36-9
Rofecoxib 162011-90-7
Tenoxicam 59804-37-4
Aspirin-dl-lysine 62952-06-1
Propacetamol Hydrochloride 66532-86-3
Nabumetone 42924-53-8
Diphenyl Pyrazolidinedione 50-33-9
Tolfenamic Acid 13710-19-5
allopurinol 315-30-0
Felbinac 572-52-9
Andrographolide 5508-58-7
Letosteine 53943-88-7
Flurbiprofen 5104-49-4
Dexketoprofen 22161-81-5
Aceclofenac 89796-99-6
acemetacin 53164-05-9
Ibuprofen lysine 57469-77-9
dexibuprofen 51146-56-6
Antipyrine 60-80-0
Metamizole Sodium 68-89-3
Diclofenac Potassium 15307-81-0
Nefopam Hydrochloride 23327-57-3
sodium salicylate 54-21-7
Naproxen 22204-53-1
Naproxen Sodium 26159-34-2
Diclofenac 15307-86-5
Diclofenac Sodium 15307-79-6
Diclofenac Diethylamine Emulgel 213-16-8
Ibuprofen 15687-27-1
ketoprofen 22071-15-4
Acetamino phen 103-90-2
Meloxicam 71125-38-7
Piroxicam 36322-90-4
Benzocaine 1994-o7-4
aspirin 50-78-2
Aminopyrine 58-15-1
Indomethacin 53-86-1
dyclonlne 536-43-6
Salicylic acid 69-72-7
pranoprofen 52549-17-4
Carisoprodol 78-44-4
zaltoprofen 89482-00-8
Lappaconite Hydrobromide 97792-45-5
Celecoxib 169590-42-5
Loxoprofen Sodium 80382-23-6
Deoxycholic acid 83-44-3
Rotundine 10097-84-4
Carisoprodol 78-44-4

The quality control process

1) Purchasing
Thorough market research, understand the price of raw materials and performance.To the procurement source to understand fully, and fully guarantee the quality of the procurement of raw materials.

2) Inspection
Four steps: sampling, sample pretreatment, measuring and data processing.

3) Producing

a) Each operator must do self-inspection of producs and make the corresponding inspection records.
b) Full-time inspectors through check the operator self-inspection, and review and sign in the corresponding record. Full-time inspection is responsible for inspection of finished product, and make the finished product incoming inspection records.

4) Before selling
Test result can be provided before selling.
Third-party detection institution is allowed if you are not satisfied with test results.

OUR ADWANTAGE:

High quality with competitive price:
1) Standard: Enterprise Standard
2) All Purity≥99%
3) We are manufacturer and can provide high quality products with factory price.

Fast and safe delivery
1) Parcel can be sent out in 24 hours after payment. Tracking number available
2) Secure and discreet shipment. Various transportation methods for your choice.
3) Customs pass rate ≥99%
4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe, and we have stock in there for transferring.

We have clients throughout the world.
1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
2) Market feedback and goods feedback will be appreciated, meeting customerss requirement is our responsibility.
3) High quality,competitive price,fast delivery ,first-class service gain the trust and praise from the customers.

If you are interested in our products, please feel free to contact me.



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