Shenzhen Wenzhi Bio-Technology Co.,Ltd
Shenzhen Wenzhi Bio-Technology Co.,Ltd
Shenzhen Wenzhi Bio-Technology Co.,Ltd Professional Supplier of Raw steroid powder & injectable & o
  • Home
  • Product Categories
    • Injectable Anabolic Steroids
    • Testosterone Steroid
    • Boldenone Steroid
    • Trenbolone Steroid
    • Masteron Steroid
    • Primobolan Steroid
    • Oral Anabolic Steroids
    • Steroid Hormones Powder
    • Prohormones Steroids
    • Female Steroids
    • Male Enhancement Steroids
    • Weight Loss Steroids
    • Anti Inflammatory Steroids
    • Local Anesthetic Agents
    • SARMS Raw Powder
    • Organic Solvents
    • Polypeptide Hormone
    • Pharmaceutical Raw Material
    • Anti Estrogen Steroids
    • Nandrolone Steroid
  • Company Profile
    • Company Introduction
    • Company News
  • Quality Control
  • Contact Us

Home>Products>Steroid Hormones Powder>Immune Suppressant Steroid Hormones Powder Tacrolimus Powder For Anti Inflammato

English
English
  • Immune Suppressant Steroid Hormones Powder Tacrolimus Powder For Anti Inflammato
  • Immune Suppressant Steroid Hormones Powder Tacrolimus Powder For Anti Inflammato

Immune Suppressant Steroid Hormones Powder Tacrolimus Powder For Anti Inflammato

  • Simeiquan
  • 521-11-9

  • China
  • GMP,SGS,UKAS,ISO
  • Negotiable
  • Negotiable
  • foil bag or as your requirement
  • Within 1-2 working days upon receipt payment
  • T/T, Western union, MoneyGram
  • 1000kgs/month
Contact NowChat Now
Shenzhen Wenzhi Bio-Technology Co.,Ltd

Shenzhen Wenzhi Bio-Technology Co.,LtdChina

  • Shenzhen Wenzhi Bio-Technology Co.,Ltd2020-07-10 09:46:19
    Welcome to my shop! Glad to serve you! Please send your question!
Price Inspection Certificate Product Specifications Company Profile

Product Details

Skype: cheryl940513 Whatsapp: +86 18771024715 Appreance: White Powder
MW: 302.45 MF: C20H30O2

Product Description

Tacrolimus Powder 
 
Tacrolimus Powder Description:
"Tacrolimus" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.
 
A macrolide isolated from the culture broth of a strain of Streptomyces tsukubaensis that has strong immunosuppressive activity in vivo and prevents the activation of T-lymphocytes in response to antigenic or mitogenic stimulation in vitro.
 
Tacrolimus (also FK-506 or Fujimycin) is an immunosuppressive drug whose main use is after organ transplant to reduce the activity of the patient’s immune system and so the risk of organ rejection. It is also used in a topical preparation in the treatment of severe atopic dermatitis, severe refractory uveitis after bone marrow transplants, and the skin condition vitiligo.
 
Tacrolimus is chemically known as a macrolide. It reduces peptidyl-prolyl isomerase activity by binding to the immunophilin FKBP-12 (FK506 binding protein) creating a new complex. This FKBP12-FK506 complex interacts with and inhibits calcineurin thus inhibiting both T-lymphocyte signal transduction and IL-2 transcription.
 
Tacrolimus is used together with other medicines to prevent the body from rejecting a transplanted organ (eg, kidney, liver, or heart). This medicine may be used with steroids, azathioprine, basiliximab, or mycophenolate mofetil. Tacrolimus belongs to a group of medicines known as immunosuppressive agents.
Tacrolimus is a very strong medicine. It can cause side effects that can be very serious, such as kidney problems. It may also decrease the bodys ability to fight infections. You and your doctor should talk about the benefits of this medicine as well as the risks of using it.
 
Tacrolimus Powder Mechanism of action:
The mechanism of action of tacrolimus in atopic dermatitis is not known. While the following have been observed, the clinical significance of these observations in atopic dermatitis is not known. It has been demonstrated that tacrolimus inhibits T-lymphocyte activation by first binding to an intracellular protein, FKBP-12.
 
A complex of tacrolimus-FKBP-12, calcium, calmodulin, and calcineurin is then formed and the phosphatase activity of calcineurin is inhibited. This prevents the dephosphorylation and translocation of nuclear factor of activated T-cells (NF-AT), a nuclear component thought to initiate gene transcription for the formation of lymphokines.
 
Tacrolimus also inhibits the transcription for genes which encode IL-3, IL-4, IL-5, GM-CSF, and TNF-, all of which are involved in the early stages of T-cell activation. Additionally, tacrolimus has been shown to inhibit the release of pre-formed mediators from skin mast cells and basophils, and to downregulate the expression of FceRI on Langerhans cells.
 
Tacrolimus Powder Usages:
Tacroz Forte Ointment (Tacrolimus) is used to treat atopic dermatitis (more commonly known as eczema). It is a topical medication which is normally prescribed for patients who have not responded successfully to other eczema medication.
 
The ointment is a type of topical calcineurin inhibitor (TCIs) that works by weakening the patient`s immune system, which as a consequence directly reduces the severity of eczema and its symptoms. It should not be used by patients who have any kind of weak immune system.
 
Tacrolimus Powder Dosage and Administration:
Tacroz Forte Ointment (Tacrolimus) is applied directly to the affected skin. Patients are normally advised to apply the ointment twice a day for a period of approximately 6 weeks in length. If no changes or improvements to your condition occur after this period, consult your physician to discuss how best to go forward.
Tacrolimus Specifications:

Product nameTacrolimus
CAS No.109581-93-3Outer Packing1KG/drum
Standard adoptedEnterprise Standard
Items of analysisSpecificationResults
DescriptionWhite or off- white powderOff- white powder
Identification (IR)Should match with working standardComplies
SolubilitySoluble in dichloromethane, slightly soluble in ethyl acetate, methanol, insoluble in waterComplies
Melting point246.0~252.0ºC246.0ºC~248.0ºC
Water by KFNot more than 0.5%0.14%
Loss on dryingNot more than 0.5%0.17%
Residue on ignitionNot more than 0.2%0.05%
Heavy MetalsNot more than 20ppmComplies
Single maximum impurityNot more than 0.5%0.34%
Total impuritiesNot more than 1.0%0.66%
Assay by HPLC98.0% -102.0%101.0%
ConclusionQualified

 
 

Place of OriginChina
Brand NameSimeiquan
CertificationISO9001, ISO14000, KOSHER,GMP
Minimum Order Quantity:10g
Price:Negotiation
courierEMS, DHL, Fedex, UPS,TNT
Payment Terms:TT, West Union, Money Gram,Bitcoin
Supply Ability:1000kg per month
Delivery date:Within 24 hours after receiving your payment
Packaging Details:Very discreet packages

 

 
Name: Cara Nalan



China Customized Inflatable Bumper Ball Game Bubble Adult Grass CE supplier

Immune Suppressant Steroid Hormones Powder Tacrolimus Powder For Anti Inflammato Images

Contact Us

Shenzhen Wenzhi Bio-Technology Co.,Ltd
Address
Phone(Working Time)
Fax
  • Shenzhen Wenzhi Bio-Technology Co.,Ltd
    • Quick question Quick question I'm very interested in your products; could you send me some detail reference information? Please send me detail product specification, thank you! May I be an agency of your products,and what's yourterms? We intend to purchase this product, would you please send me the quotation and minimum order quantity?
    What is this?This feature is Quick question function, select the corresponding question types, automatically enter the corresponding problem, remove your trouble of typing
Send Now

Product Categories

  • Injectable Anabolic Steroids
  • Testosterone Steroid
  • Boldenone Steroid
  • Trenbolone Steroid
  • Masteron Steroid
  • Primobolan Steroid
  • Oral Anabolic Steroids
  • Steroid Hormones Powder
  • Prohormones Steroids
  • Female Steroids
  • Male Enhancement Steroids
  • Weight Loss Steroids
  • Anti Inflammatory Steroids
  • Local Anesthetic Agents
  • SARMS Raw Powder
  • Organic Solvents
  • Polypeptide Hormone
  • Pharmaceutical Raw Material
  • Anti Estrogen Steroids
  • Nandrolone Steroid
More

New Products

  • Effective Mestanolone Steroid Hormones Powder Human Growth Hormone Muscle
  • White Human Growth Hormone Anti Aging 7 - Keto - Dehydroepiandrosterone CAS 566
  • Male Enhancement Steroid Hormones Powder Based Hormones Androsta - 1 17 - Dione
  • 302.41 MW Most Effective Prohormone , Synthetic Steroid Hormones 7 - Keto - DHEA
  • GMP Standard Steroid Hormones Powder 6 - Oxo / Laxogenin CAS 566-19-8
Tags:

tags1:Steroids Human Growth Hormone

Steroid Based Hormones

  • About Us|
  • Contact Us|
  • Site Map

Shenzhen Wenzhi Bio-Technology Co.,Ltd. Copyright © 2017 - 2021 All Rights Reserved.

  • Home
  • Product Categories
    • Injectable Anabolic Steroids
    • Testosterone Steroid
    • Boldenone Steroid
    • Trenbolone Steroid
    • Masteron Steroid
    • Primobolan Steroid
    • Oral Anabolic Steroids
    • Steroid Hormones Powder
    • Prohormones Steroids
    • Female Steroids
    • Male Enhancement Steroids
    • Weight Loss Steroids
    • Anti Inflammatory Steroids
    • Local Anesthetic Agents
    • SARMS Raw Powder
    • Organic Solvents
    • Polypeptide Hormone
    • Pharmaceutical Raw Material
    • Anti Estrogen Steroids
    • Nandrolone Steroid
  • Company Profile
    • Company Introduction
    • Company News
  • Quality Control
  • Contact Us